使用Stata进行meta分析实例
关键词: stata meta分析模块、stata meta分析教程、数据分析师、stata做meta分析、应用stata做meta分析
. sum
Variable | Obs Mean Std. Dev. Min Max
————-+——————————————————–
day | 7 1 0 1 1
year | 7 2005.286 7.040698 1991 2011
country | 0
study | 0
dn | 7 16.85714 11.66803 6 38
————-+——————————————————–
dm | 7 14.02571 3.834401 8.5 19
ds | 7 5.448572 3.270578 1 10
sn | 7 23.28571 14.02039 10 51
sm | 7 12.95286 4.237431 7.83 19.9
ss | 7 5.165714 2.857661 1.8 9
. list
+—————————————————————————-+
| day year country study dn dm ds sn sm ss |
|—————————————————————————-|
1. | 1 2011 中国 陈裕胜 11 14.4 1 10 12.7 1.8 |
2. | 1 2011 中国 梁道业 9 8.5 2.69 23 7.83 2.36 |
3. | 1 2009 中国 徐波 8 18.7 8.1 12 19.9 8 |
4. | 1 2007 中国 顾勤 6 12.48 6.55 14 9.04 5.3 |
5. | 1 2006 中国 杨从山 24 11.1 6.8 26 12.2 6.7 |
|—————————————————————————-|
6. | 1 2002 德国 Samir Sakka 22 14 3 27 12 3 |
7. | 1 1991 美国 Dan Schuller 38 19 10 51 17 9 |
+—————————————————————————-+
. metan dn- ss,fixed lcols( day year country) texts(200) boxsca(200) nowt
Study | SMD [95% Conf. Interval]
———————+—————————————————
1 | 1.184 0.249 2.120
1 | 0.273 -0.501 1.047
1 | -0.149 -1.045 0.747
1 | 0.606 -0.370 1.583
1 | -0.163 -0.719 0.393
1 | 0.667 0.088 1.246
1 | 0.212 -0.209 0.633
———————+—————————————————
I-V pooled SMD | 0.290 0.047 0.532
———————+—————————————————
Heterogeneity chi-squared = 9.15 (d.f. = 6) p = 0.165
I-squared (variation in SMD attributable to heterogeneity) = 34.4%
Test of SMD=0 : z= 2.34 p = 0.019
. metafunnel _ES _seES
Note: data input format theta se_theta assumed.
Begg’s test for small-study effects:
Rank correlation between standardized intervention effect and its standard error
adj. Kendall’s Score (P-Q) = 7
Std. Dev. of Score = 6.66
Number of Studies = 7
z = 1.05
Pr > |z| = 0.293
z = 0.90 (continuity corrected)
Pr > |z| = 0.368 (continuity corrected)
. metabias _ES _seES,egger
Note: data input format theta se_theta assumed.
Egger’s test for small-study effects:
Regress standard normal deviate of intervention
effect estimate against its standard error
Number of studies = 7 Root MSE = 1.269
——————————————————————————
Std_Eff | Coef. Std. Err. t P>|t| [95% Conf. Interval]
————-+—————————————————————-
slope | -.1250773 .52751 -0.24 0.822 -1.481085 1.23093
bias | 1.32596 1.609626 0.82 0.448 -2.811715 5.463634
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Test of H0: no small-study effects P = 0.448
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